To determine novel anti-inflammatory effects of MLK on resting and GM-CSF- stimulated eosinophils

4 parallel enclosed microcapillaries separated from 4 underlying microwells via a membrane with pores sizes of 2–10 μm

8 parallel enclosed microcapillaries for continuous flow cell-based assays | Fluorescent immunostaining or confocal microscopy

8 parallel enclosed microcapillaries for culturing primary endothelial cells and continuous flow cell-based assays

High throughput generation of microdroplets and monodispersed emulsions I Hydrophobic and Hydrophilic channels

Accurate flow rates which are more reproducible and consistent | culturing in growth media, or isolation from in vivo fluids

Adhesion of the thrombus to the vein wall | thrombus contraction and spontaneous lysis of the thrombus | mechanical thrombectomy (MT)

precision microfluidic pumps | Pulse free syringe pumps | Multiple independent channel pumping | Patented active flow control

Quantify cell adhesion, rolling, migration, cell-cell adhesion, platelet aggregation, thrombi formation - all under shear flow

Thrombosis | Inflammation | Atherosclerosis | Engineered microcapillaries | Automated highthroughput flow assay for shear stress experiment

Platelet adhesion and aggregation under flow | C604 alters the cell's major biophysical properties | Set the shear rate to model thrombosis

Quantify cell adhesion, rolling, migration, cell-cell adhesion, platelet aggregation, thrombi formation - all under shear flow.

Test the effect of HE-NECA and cangrelor on thrombi formation | Platelet Activation and Thrombus Formation In Vitro |

Novel microflow system | Low flow rates (5 pL min-1 to 10 μL min-1) and shear stress levels

Quantify cell adhesion, rolling, migration, cell-cell adhesion, platelet aggregation, thrombi ormation - all under shear flow.

Role of SHARPIN in regulating platelet function | Perfusing whole blood | Accumulation on collagen | Reduced linear ubiquitination

Role of different stimuli recognised to play an important part in atherosclerosis development | Leukocyte adhesion to endothelial cells |

Single-cell Analysis | Compatible with a wide variety of cell samples | microfluidic channel | Impedance Spectroscopy

Microfluidic pump | Independent flow control | 4 channel pump | Droplet Generation | Hydrodynamic flow focusing | Organ-on-chip

Automated Cell Counting | Label-free | Single-cell Analysis | High-throughput | Fast Set-up & Analysis | Impedance Spectroscopy |