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Leveraging Precision Medicine with Organs on Chip

Organs-on-a-chip have several applications of interest in the biomedical industry. This article discusses its use in the growing area of precision medicine.

We also show you how to use Cellix's 4U 4-channel Microfluidic Pump to get the best results for your organ-on-chip experiments.

Why is precision medicine a big deal?

Precision medicine gives healthcare professionals the ability to tailor therapy to a specific person. That way, each patient can receive treatment with better chances of success, [1]. Research indicates that several factors may affect how the body responds to different drugs, including:

  • Genetic and epigenetic makeup

  • Age

  • Nutrition

  • Health status

  • Environmental exposure

Unlike traditional medicine, precision medicine considers different drug response patterns among geographically and ethnically distinct populations. It tries to understand its molecular basis, [1].

With the promise of better outcomes and higher safety, it's no surprise that the precision medicine market is booming. The industry is expected to be worth $88 billion by 2022. Medical devices and drug manufacturers can benefit from this growth by targeting patients that don't respond to currently available treatments. Indeed, the whole healthcare system is likely to transform as precision medicine becomes widely available in the next few years, [1].

Precision medicine in practice

Advances in genomics and molecular biology allow professionals to select drugs or treatment protocols based on an individual's genetic profile. This helps to minimize adverse events and ensure better outcomes. Now physicians can go beyond the one-size-fits-all, prescribing to make better-informed decisions for their patients, [1].

Precision medicine also allows checking for an individual's susceptibility to certain diseases before they even appear. That way, physicians can monitor and recommend prevention measures.

The potential benefits of precision medicine are infinite, including, [1]:

  • Shifting towards a more preventive practice

  • Reducing trial-and-error prescribing

  • Avoiding adverse events

  • Increasing patient's compliance

  • Reducing the time and cost of clinical trials