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How to maintain Cellix's microfluidic Flow Sensor


Introduction

Flow Sensors for Microfluidic Pumps are designed to provide accurate and pulse-free flow rates for microfluidic applications. Flow sensors for Cellix's microfluidic pumps enable active feedback and PID control. They are ideal for microfluidic applications, where accurate and stable flow rate delivery is required resulting in superior performance. Our flow sensors are compatible with our ExiGo, UniGo and 4U microfluidic pumps.


How to handle the Flow Sensor?

Cellix's microfluidic flow sensors are highly sensitive measurement devices that should be properly handled and cleaned to ensure long term high performance. Improper cleaning (or no cleaning) may leave deposits on the internal flow channel wall that can cause measurement deviations. This should be avoided by cleaning the sensor after usage and especially before storing the sensor for longer periods.

This blog will guide you through the general cleaning protocol for Cellix’s microfluidic flow sensors and advise you on which cleaning agents to use depending on the liquid media samples you are working with.

We recommend this cleaning protocol after every use and before storing your flow sensor.

Below are some things to keep in mind for general handling of the Flow Sensor :

  • Do not allow the sensor to dry with media in the capillary tube without flushing clean first. Also try to avoid letting the filled sensor sit for extended periods (depending on your liquid).

  • Before storing the sensor, always drain the fluid, flush with cleaning agent, blow out, and dry the capillary. Sensor plugs should be installed for storage. The cleaning agent (detergent, solvent, etc.) should be chosen for its effectiveness in removing the liquid media, and compatibility with borosilicate glass.

  • In general we recommend finishing any cleaning with an acetone and/or IPA flush before letting the sensor dry out and closing it for storage. The advantage of using clean IPA is that it evaporates without residue (in contrast to acetone, for example).

  • Before storing the flow sensor, always drain the fluid:

  1. This is done easily by connecting an empty syringe and pushing air through the flow sensor. We recommend a 1mL syringe for 1.5, 7 and 80uL/min flow sensors; and a 5mL syringe for 1mL/min flow sensors.

  2. Once there are no liquid droplets emerging from the tubing, the tubing may be disconnected, and the plugs provided should be installed on the fluidic ports for storage.

Finally, Never try to clean the flow sensor by mechanical means and never put any rigid or sharp objects inside the flow sensor.


What is the cleaning procedure for the Flow Sensor?