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Getting started with Cellix's Vena8 Glass Coverslip Biochips

Vena8 Glass Coverslip Biochips: glass coverslips adhered or non-adhered glass coverslips treated/non-treated

Introduction

Vena8GCS biochips contains 8 capillaries in parallel which can be coated with a protein or seeded with cells or microbes and subsequent study of drug interaction, imaging or molecular biology studies under shear flow. Within this range of biochips; the bottom substrate is a glass coverslip which is supplied separate or supplied adhered to the chip. The glass coverslip may be non-treated or treated with chelated Cu2+ ion tethered to the high-density PEG coating. The surface of the microcapillaries are easily coated via pipetting the protein into the capillary which then binds via the poly-histidine tag.


Each 10 pack contains 80 assays. These biochips are compatible with confocal microscopy. Compatible with Mirus Evo nanopump, ExiGo, UniGo and 4U microfluidic pumps for low shear stresses of 0.1–2 dyne/cm2 (water-based solution) and 0.45–9 dyne/cm2 (whole blood) and for high shear stresses of 20–40 dyne/cm2 (water-based solution) and 90–180 dyne/cm2 (whole blood). Compatible with Kima pump for cell culture.


Vena8GCS Features:

  • High magnification; compatible with high NA oil immersion lenses.

  • Brightfield / phase contrast / fluorescent / confocal microscopy.

  • Suitable for a wide range of cell suspensions and whole blood.

  • Easy to coat microcapillaries with a range of different adhesion molecules.

  • Glass coverslip may be non-treated or treated with chelated Cu2+ ion tethered to the high-density PEG coating.

  • Shear stress / shear flow rate may be pre-set to be incrementally increased during an assay.

  • Real time imaging under flow conditions.

  • No Luer lock connections which increase dead volume.

  • Applications include, but are not limited to:

  1. Thrombosis assays; e.g. using biochips with glass coverslips treated with chelated Cu2+ ion tethered to the high-density PEG coating. Biochips perfect for high flow rates / shear stresses.

  2. Stem cell culture

  3. Biofilm applications; e.g. particularly when supplied without glass coverslip:

  4. user may attach any type of coupon to bottom of the biochip.

Performance and Technical Specifications:



So now you know the features and benefits of our Vena8 Glass Coverslip Biochips and how they works. But, if you still have questions or want to learn more, check out our website, at wearecellix.com, or contact us at info@wearecellix.com.





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