Vena8 Endothelial+

8-channel Microfluidic Cell Culture & Flow Chamber

PLUG & PLAY = LOW DEAD VOLUME with easy-to-connect tubing cables, no bulky luer connectors.

CELL CULTURE OF ENDOTHELIAL CELL MONOLAYERS IN MICROCHANNEL FLOW CHAMBERS with recirculating culture media via Kima pump.

CELL-CELL ADHESION SHEAR FLOW ASSAYS ON ENDOTHELIAL MONOLAYERS: 5 - 1,000 s   with 100µL syringe; steps of 5 s   with Exigo or Mirus Evo pumps.

COMPATIBLE WITH WIDE VARIETY OF CELL SAMPLES: whole blood, platelets, primary cells (T-cells, neutrophils, eosinophils etc.) and rare cells.

LOW SAMPLE VOLUME - even at high flow / shear rates with whole blood or cell suspensions.

REAGENT & CELL SAVINGS with only 10µL ligand/protein coating per channel (e.g. fibronectin to promote endothelial cell seeding) and only 5µL endothelial cell seeding per channel with standard pipette.

COMPATIBLE WITH STANDARD PIPETTES FOR EASY CELL SEEDING

COMPATIBLE WITH BRIGHTFIELD, PHASE CONTRAST IMAGING & FLUORESCENCE MICROSCOPY

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HOW DOES IT WORK?

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DOWNLOADS

 

APPLICATIONS

  • Cell culture of endothelial cell monolayers for shear flow experiments.

  • Cell-cell adhesion shear flow assays on endothelial cell monolayers for studies such as:

    • Cardiovascular / Atherosclerosis​:  primary monocyte adhesion to coronary artery endothelial cells.

    • Inflammation​:  THP-1 monocyte adhesion to HUVECs under flow.

    • Asthma / COPD: eosinophil adhesion studies to human lung microvascular endothelial cells (HMVEC-L).

    • Oncology - Breast Cancer:  MDA cells adhering to TNF-alpha stimulated HUVECs under shear flow.

APPLICATION VIDEOS

Application Notes:

Thrombosis / Platelet Adhesion and Aggregation:

Inflammation / Leukocyte Adhesion:

Asthma & Allergies / Eosinophil Adhesion:

Oncology / Melanoma cell adhesion & metastasis:

Bacteria / E. coli adhesion / Biofilm formation:

 

ACCESSORIES

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Microfluidic Pumps

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Tubing Sets

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Microscope Frames

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Biochip Storage

 
 

DEMONSTRATIONS & HOW TO...

 

TRAINING VIDEOS

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© 2020 By Cellix Ltd.

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Unit 1, Longmile Business Park, Longmile Road, Dublin 12, Ireland

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