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Vena8 Endothelial+

8-channel Microfluidic Cell Culture & Flow Chamber

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PLUG & PLAY = LOW DEAD VOLUME with easy-to-connect tubing cables, no bulky luer connectors.

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CELL CULTURE OF ENDOTHELIAL CELL MONOLAYERS IN MICROCHANNEL FLOW CHAMBERS with recirculating culture media via Kima pump.

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CELL-CELL ADHESION SHEAR FLOW ASSAYS ON ENDOTHELIAL MONOLAYERS: 5 - 1,000 s   with 100µL syringe; steps of 5 s   with Exigo or Mirus Evo pumps.

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COMPATIBLE WITH WIDE VARIETY OF CELL SAMPLES: whole blood, platelets, primary cells (T-cells, neutrophils, eosinophils etc.) and rare cells.

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LOW SAMPLE VOLUME - even at high flow / shear rates with whole blood or cell suspensions.

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REAGENT & CELL SAVINGS with only 10µL ligand/protein coating per channel (e.g. fibronectin to promote endothelial cell seeding) and only 5µL endothelial cell seeding per channel with standard pipette.

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COMPATIBLE WITH STANDARD PIPETTES FOR EASY CELL SEEDING

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COMPATIBLE WITH BRIGHTFIELD, PHASE CONTRAST IMAGING & FLUORESCENCE MICROSCOPY

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HOW DOES IT WORK?

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DOWNLOADS

How does it work?
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APPLICATIONS

  • Cell culture of endothelial cell monolayers for shear flow experiments.​

  • Cell-cell adhesion shear flow assays on endothelial cell monolayers for studies such as:

    • Cardiovascular / Atherosclerosis​:  primary monocyte adhesion to coronary artery endothelial cells.

    • Inflammation​:  THP-1 monocyte adhesion to HUVECs under flow.

    • Asthma / COPD: eosinophil adhesion studies to human lung microvascular endothelial cells (HMVEC-L).

    • Oncology - Breast Cancer:  MDA cells adhering to TNF-alpha stimulated HUVECs under shear flow.

APPLICATION VIDEOS

Application Notes:

Thrombosis / Platelet Adhesion and Aggregation:

Inflammation / Leukocyte Adhesion:

Asthma & Allergies / Eosinophil Adhesion:

Oncology / Melanoma cell adhesion & metastasis:

Bacteria / E. coli adhesion / Biofilm formation:

Applications

ACCESSORIES

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Microfluidic Pumps

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Tubing Kits

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Microscope Frames

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Biochip Storage

Accessories
Demonstration videos

DEMONSTRATIONS & HOW TO...