Vena8 Endothelial+
8-channel Microfluidic Cell Culture & Flow Chamber







PLUG & PLAY = LOW DEAD VOLUME with easy-to-connect tubing cables, no bulky luer connectors.
​
CELL CULTURE OF ENDOTHELIAL CELL MONOLAYERS IN MICROCHANNEL FLOW CHAMBERS with recirculating culture media via Kima pump.
​
CELL-CELL ADHESION SHEAR FLOW ASSAYS ON ENDOTHELIAL MONOLAYERS: 5 - 1,000 s with 100µL syringe; steps of 5 s with Exigo or Mirus Evo pumps.
​
COMPATIBLE WITH WIDE VARIETY OF CELL SAMPLES: whole blood, platelets, primary cells (T-cells, neutrophils, eosinophils etc.) and rare cells.
​
LOW SAMPLE VOLUME - even at high flow / shear rates with whole blood or cell suspensions.
​
REAGENT & CELL SAVINGS with only 10µL ligand/protein coating per channel (e.g. fibronectin to promote endothelial cell seeding) and only 5µL endothelial cell seeding per channel with standard pipette.
​
COMPATIBLE WITH STANDARD PIPETTES FOR EASY CELL SEEDING
​
COMPATIBLE WITH BRIGHTFIELD, PHASE CONTRAST IMAGING & FLUORESCENCE MICROSCOPY
-1
-1


HOW DOES IT WORK?

Cell-cell adhesion to endothelial cell monolayer under shear flow

Easy to coat with protein or seed cells using standard pipette

Easy-to-connect tubing plugs directly into inlet of biochip; no dead volume

Cell-cell adhesion to endothelial cell monolayer under shear flow
DOWNLOADS

APPLICATIONS
-
Cell culture of endothelial cell monolayers for shear flow experiments.​
-
Cell-cell adhesion shear flow assays on endothelial cell monolayers for studies such as:
-
Cardiovascular / Atherosclerosis​: primary monocyte adhesion to coronary artery endothelial cells.
-
Inflammation​: THP-1 monocyte adhesion to HUVECs under flow.
-
Asthma / COPD: eosinophil adhesion studies to human lung microvascular endothelial cells (HMVEC-L).
-
Oncology - Breast Cancer: MDA cells adhering to TNF-alpha stimulated HUVECs under shear flow.
-
APPLICATION VIDEOS
Application Notes:
Thrombosis / Platelet Adhesion and Aggregation:
Inflammation / Leukocyte Adhesion:
Asthma & Allergies / Eosinophil Adhesion:
Oncology / Melanoma cell adhesion & metastasis:
Bacteria / E. coli adhesion / Biofilm formation: