VenaT4

Organ-on-Chip, Cell culture on-chip, chemotaxis, transmigration & invasion assays under flow.

 
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PLUG & PLAY = LOW DEAD VOLUME with easy-to-connect tubing cables, no bulky luer connectors.

ORGAN-ON-CHIP FOR HEART, LUNG, BRAIN, KIDNEY, LIVER & MORE with long-term media / reagent perfusion in standard CO2 incubators.  Pressure and flow controlled with Cellix's UniGo or 4U pumps.

CHEMOTAXIS, TRANSMIGRATION & INVASION ASSAYS UNDER FLOW: cells adhere from flow and transmigrate through embedded microporous membrane (2-10 μm pore sizes) into underlying microwell containing chemoattractant or "organ".

COMPATIBLE WITH WIDE VARIETY OF CELL TYPES

LOW SAMPLE VOLUME - even at high flow / shear rates for whole blood with ExiGo or Mirus pumps or cell suspensions with ExiGo, Mirus, UniGo, 4U and Kima pumps.

REAGENT SAVINGS with only 10µL ligand/protein coating per channel (e.g. VWF, collagen, VCAM, ICAM etc.) with standard pipette.

COMPATIBLE WITH STANDARD PIPETTES FOR EASY PROTEIN COATING OR CELL SEEDING

COMPATIBLE WITH IMMUNOFLUORESCENCE MICROSCOPY

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HOW DOES IT WORK?

VenaT4 Biochip detail
VenaT4 Biochip detail

Chemotaxis, Transmigration & Invasion assay

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VenaT4_coating biochip with pipette
VenaT4_coating biochip with pipette

Easy to coat with protein using standard pipette

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VenaT4 Biochip detail
VenaT4 Biochip detail

Chemotaxis, Transmigration & Invasion assay

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DOWNLOADS

 
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APPLICATIONS

  • Organ-on-chip studies:  Culture heart, lung, liver, kidney or other organ cells in 4 microwells-on-chip with media perfusion provided by Cellix's 4U or UniGo pumps.  Subsequently flow drugs or cells through the overlaying microchannel enabling drug-concentration studies or transmigration and invasion studies into your organ of choice.

  • Chemotaxis, Transmigration & Invasion Assays: Fill microwells with gels containing chemoattractants of interest.  Flow cells through overlaying microchannel and study cell adhesion, chemotaxis, transmigration and invasion into underlying microwell.

 

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DEMONSTRATIONS & HOW TO...

 

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